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AN ORGAN WHICH CAN BE GROWN |
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Reconstruct epidermis in an culture dish |
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Developed first and foremost for grafting major burns, reconstructed skin also forms a valuable model for testing new pharmaceutical or cosmetic products. These models allow evaluation of good tolerance and efficacy of products with very precise criteria; they therefore provide alternative methods to animal experimentation. Since 1979, the year of the first reconstructed epidermis, different types of model have been developed to reconstruct in vitro either the structure of the epidermis, or the dermis, or a dermo-epidermal structure. These are tools not only for cosmetics but also for fundamental research as L'Oral researchers have recently created a model with the characteristics of the skin of "moon children" who suffer from the rare genetic disease Xeroderma Pigmentosum.
For any additional information you can visit the new Web site of L'Oréal Research dedicated to the thematic of reconstructed skins (http://www.invitroskin.com) and its industrial centre for cutaneous engineering, EPISKIN SNC:
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