11.03.2024 - Research and Innovation

Clichy, 11 March 2024 – L’Oréal Groupe today announced the launch of MelasylTM, a breakthrough molecule designed to address localized pigmentation issues that lead to age spots and post-acne marks. According to a landmark, worldwide epidemiological study on pigmentary disorders, half of all people report having at least one skin 
pigmentation issue1. L’Oréal formulations containing the new proprietary ingredient work inclusively, across all skin tones, to address pigmented marks on the skin and improve their appearance. Melasyl is the result of rigorous tests involving 121 scientific studies.


Cosmetic products formulated with multi-patented Melasyl help provide a more even, natural skin tone, addressing even the most persistent marks. Eighteen years of research have culminated in the introduction of Melasyl, which is now available in La Roche Posay’s Mela B3 franchise, including MelaB3 serum and MelaB3 SPF30. L’Oréal Paris and Vichy will follow with future product launches, expanding consumer access to expert formulations containing the new ingredient. 

“With half of all people reporting skin pigmentation issues and a third of these experiencing lower quality of life as a result, the impact of visible spots or post-acne marks is clearly more than skin-deep,” said Anne Colonna, Global Head of Advanced Research at L’Oréal Groupe. “Melasyl is a first-of-its kind ingredient that helps to address localized skin pigmentation issues, with proven efficacy and wide accessibility that will enable more people to regain their selfconfidence.”Melanin enables the vast spectrum of human skin tones in all their diversity, with melanin production increasing following sun exposure to protect skin cells. Many factors can upset normal melanin production, which can lead to localized pigmentation issues such as age spots and post-inflammatory marks. L’Oréal formulations containing Melasyl improve the appearance of existing dark spots, including persistent ones, with clinically demonstrated efficacy and safety across all skin tones.

For over a century, L’Oréal has been a leader in advanced sciences for beauty, with 35 years of dedicated research into skin pigmentation. Melasyl was first presented at the World Congress of Dermatology 2023 in Singapore, alongside the first worldwide epidemiological study on pigmentary disorders. Melasyl was recently featured at the American Academy of Dermatology’s annual meeting in San Diego from March 8-12, 2024. 



About L’Oréal

For over 110 years, L’Oréal, the world’s leading beauty player, has devoted itself to one thing only: fulfilling the beauty aspirations of consumers around the world. Our purpose, to create the beauty that moves the world, defines our approach to beauty as inclusive, ethical, generous and committed to social and environmental sustainability. With our broad portfolio of 37 international brands and ambitious sustainability commitments in our L’Oréal for the Future programme, we offer each and every person around the world the best in terms of quality, efficacy, safety, sincerity and responsibility, while celebrating beauty in its infinite plurality.

With 87 400 committed employees, a balanced geographical footprint and sales across all distribution networks (e-commerce, mass market, department stores, pharmacies, hair salons, branded and travel retail), in 2022 theGroup generated sales amounting to 38.26 billion euros. With 20 research centers across 11 countries around the world and a dedicated Research and Innovation team of over 4 000 scientists and 5 500 tech and digital professionals, L’Oréal is focused on inventing the future of beauty and becoming a Beauty Tech powerhouse.

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